Beetroot from non-GMO beetroot powder that helps supports Nitric Oxide production through the nitrate-nitrite pathway.
Hawthorn Berry Extract contains high levels of antioxidants (polyphenols) that help activate the key enzyme eNOS, which helps your body quickly convert L-arginine to Nitric Oxide. It also helps reduce nitrite to Nitric Oxide.
Sodium Nitrite is quickly converted to Nitric Oxide by hawthorn berry extract and has clinically significant vasodilator activity.
L-citrulline is an effective substitute source for L-arginine, which eNOS converts to Nitric Oxide. It also inhibits arginase, which removes L-arginine from circulation. This then reduces Nitric Oxide production.
Vitamin B12 reduces direct inhibition of eNOS by homocysteine and production of ADMA (asymmetrical dimethyl-arginine), and helps replenish tetrahydrobiopterin.
Vitamin C helps prevent removal of Nitric Oxide by free radicals and removes free radicals that inhibit eNOS.