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We recognized a fundamental challenge with berberine supplementation: its poor oral bioavailability severely limited its potential benefits. While berberine showed impressive research results for metabolic health and cellular function, users needed high doses to achieve meaningful effects. The supplement industry largely ignored this bioavailability challenge, offering berberine products that delivered suboptimal results.

preferably with a meal, or as directed by a healthcare professional.

• Supports Healthy Lipid And Glucose Metabolism: Promotes healthy lipid metabolism and glucose utilization through AMPK activation, which increases glucose uptake through glycolysis while supporting glucose production via gluconeogenesis.
• Supports Cognitive Function: Activates sigma-1 receptors to support BDNF levels and optimize NMDA activity, while supporting acetylcholine levels by regulating acetylcholinesterase enzyme activity.
• Supports Immune System Function: Provides comprehensive immune support through berberine's traditional use in Ayurveda combined with silymarin's antioxidant activity for enhanced immune defense.
• Supports Healthy Neurological Function: Supports cellular health through telomerase regulation and enhanced BDNF activity, which research indicates helps maintain optimal memory formation and overall brain function.

hypromellose (vegetable capsule), microcrystalline cellulose, silicon dioxide. No added artificial colors, flavors, or preservatives